| Identification | Back Directory | [Name]
4-Chloro-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine | [CAS]
208459-81-8 | [Synonyms]
6-Chloro-7-phenyl-7-deazapurine
4-Chloro-5-phenyl-1H-pyrrolo[2,3-d]pyrimidine
4-Chloro-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine | [Molecular Formula]
C12H8ClN3 | [MOL File]
208459-81-8.mol | [Molecular Weight]
230 |
| Questions and Answers (Q&A) | Back Directory | [Description]
4-Chloro-5-phenyl-7H-pyrrolo [2, 3-d] pyrimidine is a kind of pyrrolopyrimidine deriviative. Pyrrolopyrinmidine derivatives have been shown to exhibit promoting antihyperglycemic activity, being comparable to a well-known standard antihyperglycemic drug, Glimepiride. Pyrrolo [2, 3-d] pyrimidine derivatives have an important role in modern medicine and have shown marked antitumor and antiviral activity.
| [References]
Mohamed, M. S., et al. "Synthesis and Evaluation of Novel Pyrroles and Pyrrolopyrimidines as Anti-Hyperglycemic Agents." Biomed Research International 2014.1(2014):249780.
Babi?, Maja Stipkovi?, et al. "N-1 alkyl, 1, 2, 3-triazolyl and C-5 alkynyl cytosine, uracil an C-6 alkyl pyrrolo [2, 3-d] pyrimidine derivatives: synthesis, cytostatic and antibacterial evaluations." Tetrahedron Symposium Challenges in Biological, Bioorganic, Organic & Medicinal Chemistrysitges, Španjolska 2016.
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