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20897-92-1

20897-92-1 Structure

20897-92-1 Structure
IdentificationBack Directory
[Name]

15-EPI PROSTAGLANDIN A1
[CAS]

20897-92-1
[Synonyms]

15-EPI PROSTAGLANDIN A1
ZMSIOGLWJPSSFG-AHUSATQRSA-N
9-OXO-15R-HYDROXY-PROSTA-10,13E-DIEN-1-OIC ACID
Prosta-10,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15R)- (9CI)
[Molecular Formula]

C20H32O4
[MDL Number]

MFCD00036681
[MOL File]

20897-92-1.mol
[Molecular Weight]

336.47
Chemical PropertiesBack Directory
[Boiling point ]

510.7±50.0 °C(Predicted)
[density ]

1.086±0.06 g/cm3(Predicted)
[solubility ]

DMF: >50 mg/ml; DMSO: >75 mg/ml; Ethanol: >100 mg/ml; PBS (pH 7.2): >2.4 mg/ml
[pka]

4.77±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H336
[Precautionary statements ]

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

15-epi PGA1 is the 15(R) stereoisomer of PGA1. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients. There are no published reports on the biological activity of 15-epi PGA1 at this time.
[Uses]

15-epi PGA1 is the 15(R) stereoisomer of PGA1. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive patients. There are no published reports on the biological activity of 15-epi PGA1 at this time.
[Uses]

15-epi Prostaglandin A1 is a naturally occurring prostaglandin used in hypertension studies.
[Definition]

ChEBI:15-epi-PGA1 is a prostanoid.
[References]

[1] L R KRAKOFF. Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin.[J]. Clinical science and molecular medicine. Supplement, 1975, 2: 311s-313s. DOI: 10.1042/cs048311s
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