| Identification | Back Directory | [Name]
6-B-HYDROXY EPLERENONE | [CAS]
209253-80-5 | [Synonyms]
6--Hydroxy Eplerenone
6β-Hydroxy Eplerenone
Eplerenone Impurity 11
6-B-HYDROXY EPLERENONE
6-beta-Hydroxy Eplerenone
Eplerenone 6-β-Hydroxy Analog
Eplerenone 6-beta-Hydroxy Analog
(6β,7α,11α,17α)-9,11-Epoxy-6,17-dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester
Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-6,17-dihydroxy-3-oxo-, γ-lactone, methyl ester, (6β,7α,11α,17α)- | [Molecular Formula]
C24H30O7 | [MOL File]
209253-80-5.mol | [Molecular Weight]
430.49 |
| Chemical Properties | Back Directory | [Melting point ]
128-135°C | [Boiling point ]
642.7±55.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.16±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone . It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4. | [Chemical Properties]
White to Off-White Solid | [Uses]
6-B-HYDROXY EPLERENONE is a metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. 6-B-HYDROXY EPLERENONE is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
| [Uses]
A metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. | [storage]
Store at -20°C | [References]
[1] CHYUNG S COOK. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5.[J]. Drug Metabolism and Disposition, 2002, 30 12: 1344-1351. DOI: 10.1124/dmd.30.12.1344 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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