| Chemical Properties | Back Directory | [Boiling point ]
1695.323±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.446±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
1.833±0.10(predicted) | [Sequence]
DOTA-{d-Phe}-Cys-Phe-{d-Trp}-Lys-Thr-Cys-{Threoninol} (Disulfide bridge: Cys2-Cys7) |
| Hazard Information | Back Directory | [Uses]
DOTA-Octreotide is composed of chelator DOTA and Octreotide (HY-P0036). DOTA-Octreotide is used for research of cancer, through combination with radioactive elements. DOTA-Octreotide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs)[1]. | [IC 50]
RDC Peptide | [References]
[1] Bodei L, et al., Receptor radionuclide therapy with 90Y-[DOTA]0-Tyr3-octreotide (90Y-DOTATOC) in neuroendocrine tumours. Eur J Nucl Med Mol Imaging. 2004 Jul;31(7):1038-46. DOI:10.1007/s00259-004-1571-4 |
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