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2095417-68-6

2095417-68-6 Structure

2095417-68-6 Structure
IdentificationBack Directory
[Name]

1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil
[CAS]

2095417-68-6
[Synonyms]

1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil
1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil
2,?4(1H,?3H)?-?Pyrimidinedione, 1-?(5,?6-?dideoxy-?2-?O-?methyl-?6-?phosphono-?β-?D-?ribo-?hexofuranosyl)?-
[Molecular Formula]

C11H17N2O8P
[MOL File]

2095417-68-6.mol
[Molecular Weight]

336.24
Chemical PropertiesBack Directory
[density ]

1.62±0.1 g/cm3(Predicted)
[pka]

2.46±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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