| Identification | Back Directory | [Name]
Stafib-2 | [CAS]
2097938-74-2 | [Synonyms]
Stafib-2
Benzamide, 4-[2-[[[3,4-bis(phosphonooxy)phenyl]methyl]amino]-2-oxoethoxy]-N-(4-phenoxyphenyl)- | [Molecular Formula]
C28H26N2O12P2 | [MDL Number]
MFCD34167492 | [MOL File]
2097938-74-2.mol | [Molecular Weight]
644.46 |
| Chemical Properties | Back Directory | [density ]
1.549±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 50 mg/mL (77.58 mM; Need ultrasonic) | [form ]
Solid | [pka]
1.05±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC50 of 82 nM and 1.7 μM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeability[1]. | [References]
[1] Elumalai N, et, al. Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b. Sci Rep. 2017 Apr 11;7(1):819. DOI:10.1038/s41598-017-00920-3 |
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cjbscvictory
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13348960310 13348960310 |
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https://www.weikeqi-biotech.com/ |
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nanjing
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13376082704 13376082704 |
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www.linye-e.com/ |
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