ChemicalBook--->CAS DataBase List--->209860-89-9

209860-89-9

209860-89-9 Structure

209860-89-9 Structure
IdentificationBack Directory
[Name]

Tafluprost ethyl ester
[CAS]

209860-89-9
[Synonyms]

Tafluprost ethyl ester
SPWJIEVPQKMQPO-MSHHKXPZSA-N
Tafluprost ethyl ester Exclusive
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, ethyl ester, (5Z)-
[Molecular Formula]

C24H32F2O5
[MOL File]

209860-89-9.mol
[Molecular Weight]

438.5
Chemical PropertiesBack Directory
[Boiling point ]

546.6±50.0 °C(Predicted)
[density ]

1.202±0.06 g/cm3(Predicted)
[solubility ]

DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
[form ]

10% wt/wt in ethanol
[pka]

14.48±0.70(Predicted)
[Cosmetics Ingredients Functions]

HAIR CONDITIONING
[InChIKey]

SPWJIEVPQKMQPO-MSHHKXPZSA-N
[SMILES]

C(OCC)(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/C(F)(F)COC1=CC=CC=C1
Safety DataBack Directory
[Symbol(GHS) ]


GHS02
[Signal word ]

Danger
[Hazard statements ]

H225
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Uses]

Tafluprost ethyl ester (AFP-175) is a derivative of Prostaglandin F2α (PGF2α) (HY-12956). Tafluprost ethyl ester is an agonist for prostaglandin FP receptor, and exhibits miotic effect[1].
[References]

[1] Nakajima T, et al., New fluoroprostaglandin F(2alpha) derivatives with prostanoid FP-receptor agonistic activity as potent ocular-hypotensive agents. Biol Pharm Bull. 2003 Dec;26(12):1691-5. DOI:10.1248/bpb.26.1691
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