| Identification | Back Directory | [Name]
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(2,5-dihydro-2-methylene-5-oxo-1H-pyrrol-1-yl)hexahydro-2-oxo-, (3aR,4R,6aS)- | [CAS]
2100288-18-2 | [Synonyms]
L-Biotin-NH-5MP
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(2,5-dihydro-2-methylene-5-oxo-1H-pyrrol-1-yl)hexahydro-2-oxo-, (3aR,4R,6aS)- | [Molecular Formula]
C15H20N4O3S | [MOL File]
2100288-18-2.mol | [Molecular Weight]
336.41 |
| Hazard Information | Back Directory | [Uses]
L-Biotin-NH-5MP is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation[1]. | [References]
[1] Yingqian Zhang, et al. Thiol Specific and Tracelessly Removable Bioconjugation via Michael Addition to 5-Methylene Pyrrolones. J Am Chem Soc. 2017 May 3;139(17):6146-6151. DOI:10.1021/jacs.7b00670 |
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