| Identification | Back Directory | [Name]
Ald-PEG1-t-butyl ester | [CAS]
2100306-48-5 | [Synonyms]
Ald-PEG1-C2-Boc
Ald-PEG1-t-butyl ester
tert-butyl 3-(3-oxopropoxy)propanoate | [Molecular Formula]
C10H18O4 | [MDL Number]
MFCD30723216 | [MOL File]
2100306-48-5.mol | [Molecular Weight]
202.25 |
| Hazard Information | Back Directory | [Description]
Ald-PEG1-t-butyl ester can react with hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The t-butyl ester can be removed under acidic conditions for further conjugation. | [Uses]
Ald-PEG1-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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