| Identification | Back Directory | [Name]
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid | [CAS]
2100306-50-9 | [Synonyms]
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid | [Molecular Formula]
C38H45N5O13S | [MDL Number]
MFCD30723236 | [MOL File]
2100306-50-9.mol | [Molecular Weight]
811.86 |
| Chemical Properties | Back Directory | [InChIKey]
VGMWZPOXYYJXCA-UHFFFAOYSA-N | [SMILES]
O=C1C2=CC(NC(=S)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(=O)O)=CC=C2C2(C3=CC=C(O)C=C3OC3=CC(O)=CC=C23)O1 |
| Hazard Information | Back Directory | [Description]
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid contains azide, fluorescein and carboxylic acid moieties. The azide can react with alkynes in copper-catalyzed Click Chemistry. Fluorescein is a universal dye which is used for dye labeling. The carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU. The hydrophilic PEG linker increases the compounds water solubility in aqueous media. | [Uses]
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker which contains azide, fluorescein and carboxylic acid moieties. N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs |
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