| Identification | Back Directory | [Name]
Methoxycarbonyl-peg4-t-butyl ester | [CAS]
2100306-74-7 | [Synonyms]
Boc-PEG4-methyl propionate
Methoxycarbonyl-peg4-t-butyl ester
4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) 16-methyl ester | [Molecular Formula]
C17H32O8 | [MDL Number]
MFCD30723232 | [MOL File]
2100306-74-7.mol | [Molecular Weight]
364.43 |
| Hazard Information | Back Directory | [Description]
Methoxycarbonyl-PEG4-t-butyl ester is a PEG species with t-butyl protected carboxyl group and mono-methyl ester moieties. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG linker increases the compound's water solubility in aqueous environments. | [Uses]
Boc-PEG4-methyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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