| Identification | Back Directory | [Name]
Cephalexin-d5 | [CAS]
2101505-56-8 | [Synonyms]
Cefalexin-d5
2H5]-Cephalexin
Cephalexin-d5
DISCONTINUED, offer C256802 | [Molecular Formula]
C16H7D10N3O4S | [MOL File]
2101505-56-8.mol | [Molecular Weight]
352.42 |
| Hazard Information | Back Directory | [Uses]
Cephalexin-d5 is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al[1]. | [IC 50]
β-lactam | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Cefalexin
[3] Hongbaek Cho, et al. Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery. Cell. .?2014 Dec 4;159(6):1300-11. DOI:10.1016/j.cell.2014.11.017 |
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