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21028-20-6

21028-20-6 Structure

21028-20-6 Structure
IdentificationBack Directory
[Name]

3-METHYLCYTIDINE METHOSULFATE
[CAS]

21028-20-6
[Synonyms]

3-METHYLCYTIDINE METHOSULFATE
N3-Methylcytidine methosulfate
3-Methylcytidine Mono(Methyl Sulfate) Salt
((2R,3S,4R,5R)-5-(4-Amino-3-methyl-2-oxo-2,3-dihydropyrimidin-1(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl methyl sulfate
[Molecular Formula]

C11H19N3O9S
[MDL Number]

MFCD00038739
[MOL File]

21028-20-6.mol
[Molecular Weight]

369.35
Chemical PropertiesBack Directory
[Melting point ]

230-233°C
[storage temp. ]

−20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

29349990
Hazard InformationBack Directory
[Description]

3-Methylcytidine (methosulfate) is a cytidine derivative used as an internal standard for HPLC. 3-Methylcytidine is a common epigenetic modification in tRNA but its role in the cell has not been defined. 3-Methylcytidine has been investigated as a potential biomarker for cancer and was significantly elevated in the urine of breast cancer patients.
[Chemical Properties]

White Solid
[Uses]

Cytidine derivative.
[References]

[1] SONIA D’SILVA  Eric M P  Steffen J Haider. A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop.[J]. RNA, 2011, 17 6: 1100-1110. DOI: 10.1261/rna.2652611
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