| Identification | Back Directory | [Name]
1D-MYO-INOSITOL-1,3,4,5-TETRAKISPHOSPHATE, (NA+ SALT) | [CAS]
210488-61-2 | [Synonyms]
octasodium
INS(1,3,4,5)P4 (NA+ SALT)
QYQMPPDYTHNACQ-ZOJXHACUSA-F
INS(1,3,4,5)IP4 (SODIUM SALT)
D-MYO-INOSITOL-1,3,4,5-TETRAPHOSPHATE SODIUM SALT
1D-MYO-INOSITOL-1,3,4,5-TETRAKISPHOSPHATE, (NA+ SALT)
D-myo-Inositol-1,3,4,5-tetrakis(phosphate) octasodium salt
D-MYO-INOSITOL-1,3,4,5-TETRAKIS(DIHYDROGEN PHOSPHATE), OCTASODIUM SALT
[(1R,2S,4S,5S)-2,4-dihydroxy-3,5,6-triphosphonatooxycyclohexyl] phosphate | [Molecular Formula]
C6H8Na8O18P4 | [MDL Number]
MFCD00153818 | [MOL File]
210488-61-2.mol | [Molecular Weight]
675.93 |
| Hazard Information | Back Directory | [Description]
D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell. | [Uses]
D-myo-Inositol-1,3,4,5-tetraphosphate sodium is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. | [References]
[1] D. BILLINGTON. Synthesis of myo-inositol 1-phosphate and 4-phosphate, and of their individual enantiomers[J]. Journal of The Chemical Society, Chemical Communications, 1987, 6 10-11: 314-316. DOI: 10.1039/c39870000314
[2] D COMMUNI C E V Vanweyenberg. Purification and biochemical properties of a high-molecular-mass inositol 1,4,5-trisphosphate 3-kinase isoenzyme in human platelets.[J]. Biochemical Journal, 1994, 298 Pt 3: 669-673. DOI: 10.1042/bj2980669
[3] ANDREAS LüCKHOFF David E C. Inositol 1,3,4,5-tetrakisphosphate activates an endothelial Ca2+-permeable channel[J]. Nature, 1992, 355 6358: 356-358. DOI: 10.1038/355356a0 |
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