| Identification | Back Directory | [Name]
1′-[(4-Bromophenyl)methyl]spiro[cyclopentane-1,2′-[2H]indol]-3′(1′H)-one | [CAS]
2107978-22-1 | [Synonyms]
MAO-B-IN-23
1′-[(4-Bromophenyl)methyl]spiro[cyclopentane-1,2′-[2H]indol]-3′(1′H)-one
Spiro[cyclopentane-1,2′-[2H]indol]-3′(1′H)-one, 1′-[(4-bromophenyl)methyl]- | [Molecular Formula]
C19H18BrNO | [MOL File]
2107978-22-1.mol | [Molecular Weight]
356.26 |
| Hazard Information | Back Directory | [Uses]
MAO-B-IN-23 (Compound 11f) is a reversible and competitive MAO-B inhibitor (IC50: 1.44 μM, Ki: 0.51 μM)[1]. | [References]
[1] Perumal K, et al. An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases. RSC Adv. 2023 Aug 22;13(36):24925-24935. DOI:10.1039/d3ra03641c |
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