| Identification | Back Directory | [Name]
Cy5.5 | [CAS]
210892-23-2 | [Synonyms]
Cy5.5
Sulfo-Cy5.5
Cy5.5, >97%
Cy5 diacid, SE
Sulfo-Cyanine5.5
Bis Benzimide Hoechst NO33258
Bis Benzlimide Hoechst NO33342
Sulfo Cy5.5 Carboxylic acids(ethyl)
2-((1E,3E,5E)-5-(3-(5-Carboxypentyl)-1,1-diMethyl-1H-benzo[e]indol-2(3H)-ylidene)penta-1,3-dienyl)-3-ethyl-1,1-diMethyl-1H-benzo[e]indoliuM chloride
2-(5-(3-(5-carboxypentyl)-1,1-dimethyl-6,8-disulfo-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-3-ethyl-1,1-dimethyl-8-sulfo-1H-benzo[e]indol-3-ium-6-sulfonate | [Molecular Formula]
C41H44N2O14S4 | [MDL Number]
MFCD31560494 | [MOL File]
210892-23-2.mol | [Molecular Weight]
917.053 |
| Chemical Properties | Back Directory | [solubility ]
易溶于DMSO，DMF等有机溶剂，极易溶于水 | [form ]
Solid | [color ]
Purple to purplish red | [Appearance]
Dark blue solid | [ex/em]
678/706 nm (PBS buffer) | [ε(extinction coefficient)]
211000 L⋅mol−1⋅cm−1 | [Φ(quantum yield)]
0.21 | [InChIKey]
LIZDKDDCWIEQIN-UHFFFAOYSA-N | [SMILES]
CC1(C(N(CCCCCC(=O)O)C2=CC=C3C(=CC(S(O)(=O)=O)=CC3=C12)S(O)(=O)=O)=CC=CC=CC1C(C2=C3C=C(S(O)(=O)=O)C=C(S([O-])(=O)=O)C3=CC=C2[N+]=1CC)(C)C)C |
| Hazard Information | Back Directory | [Description]
Cy5.5 is a type of cyano dye, the definition of cyano is synthetic dye, in which nitrogen and part of the conjugated chain usually form part of a heterocyclic ring system, such as imidazole, pyridine, pyrole, quinoline and thiazole. cyano group Dyes are used in industrial biotechnology (labeling, analysis, biomedical imaging). | [Uses]
Cy5.5 (Sulfo-Cyanine5.5) is a near-infrared fluorescent dye (Ex=673 nm, Em=707 nm) used to label biomolecules such as peptides, proteins and oligonucleotides. | [in vivo]
Cy5.5-labeled factor VIIa is developed for imagining cancer. Cy5.5 labeled with these targeting proteins specifically localize to the tumor xenografts for at least 14 days but unconjugated Cy5.5 does not localize to any xenografts or organs. This method of imaging anti-tissue factor in the tumor VECs may be useful in detecting primary tumors and metastases as well as monitoring in vivo therapeutic responses[1]. pH/temperature sensitive magnetic nanogels conjugated with Cy5.5-labled lactoferrin (Cy5.5-Lf-MPNA nanogels) are developed as a promising contrast agent for preoperative MRI and intraoperative fluorescence imaging of glioma[2]. |
|
|