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2109414-84-6

2109414-84-6 Structure

2109414-84-6 Structure
IdentificationBack Directory
[Name]

CHIR 99021 dihydrochloride
[CAS]

2109414-84-6
[Synonyms]

CHIR 99021 dihydrochloride
CHIR-99021 2HCl (CT99021 dihydrochloride)
[Molecular Formula]

C22H19Cl3N8
[MOL File]

2109414-84-6.mol
[Molecular Weight]

501.8
Hazard InformationBack Directory
[Uses]

Laduviglusib;CHIR 99021;CHIR99021;CHIR-99021;CT99021;CT 99021;CT-99021
[References]

[1] Ring DB, et al. Selective glycogen synthase kinase 3 inhibitors potentiate activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95. DOI:10.2337/diabetes.52.3.588
[2] Naujok O, et al. Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors.BMC Res Notes. 2014 Apr 29;7:273. DOI:10.1186/1756-0500-7-273
[3] Ye S, et al. Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains. PLoS One. 2012;7(4):e35892. DOI:10.1371/journal.pone.0035892
2109414-84-6 suppliers list
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