2110449-01-7

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2110449-01-7 Structure

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[Description] Ald-Ph-PEG3-O-NH-Boc is a Boc-protected aminooxy PEG reagent. The aldehyde group is reactive with aminooxy molecules. Boc-protected aminooxy can be deprotected under mild acidic conditions for further conjugation.
[Uses] Ald-Ph-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

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