| Identification | Back Directory | [Name]
2-Propanesulfonamide, N-[2-(2'-fluoro[1,1'-biphenyl]-4-yl)propyl]- | [CAS]
211311-39-6 | [Synonyms]
AMPA receptor modulator-3
AMPA receptor potentiator
2-Propanesulfonamide, N-[2-(2'-fluoro[1,1'-biphenyl]-4-yl)propyl]- | [Molecular Formula]
C18H22FNO2S | [MOL File]
211311-39-6.mol | [Molecular Weight]
335.44 |
| Chemical Properties | Back Directory | [Boiling point ]
460.6±55.0 °C(Predicted) | [density ]
1.161±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (745.29 mM; Need ultrasonic) | [form ]
Solid | [pka]
11.19±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
LY392098 is a AMPA receptor potentiator. | [Uses]
AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM). AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory[1][2]. | [storage]
Store at -20°C | [References]
[1] Kasper Harps?e, et al. Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. J Mol Graph Model. 2008 Jan;26(5):874-83. https://pubmed.ncbi.nlm.nih.gov/17644444/ DOI:10.1021/jm0002836 |
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