| Identification | Back Directory | [Name]
Benzamide, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-hydroxy- | [CAS]
212631-56-6 | [Synonyms]
Benzamide, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-hydroxy- | [Molecular Formula]
C13H8F3IN2O2 | [MOL File]
212631-56-6.mol | [Molecular Weight]
408.11 |
| Hazard Information | Back Directory | [Uses]
MEK ligand-2, a MEK1 and MEK2 inhibitor, is a ligand for target protein for PROTAC of MS934 (HY-153863). MS934 is a VHL-recruiting MEK 1/2 PROTAC degrader[1]. | [References]
[1] Hu J, et al. Potent and Selective Mitogen-Activated Protein Kinase Kinase 1/2 (MEK1/2) Heterobifunctional Small-molecule Degraders. J Med Chem. 2020 Dec 24;63(24):15883-15905. DOI:10.1021/acs.jmedchem.0c01609 |
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