Identification | Back Directory | [Name]
JANELIA FLUOR 669, SE | [CAS]
2127150-20-1 | [Synonyms]
JF669, SE JANELIA FLUOR 669, SE 1-[7-(1-Azetidinyl)-10-[2-Carboxy-5-[(2-(2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl]thio-3,4,6-trifluorophenyl]-9,9-dimethyl-9-silaanthracen-2(9H)-ylidene]azetidinium, inner salt | [Molecular Formula]
C34H30F3N3O6SSi | [MDL Number]
MFCD31619141 | [MOL File]
2127150-20-1.mol | [Molecular Weight]
693.77 |
Hazard Information | Back Directory | [Description]
Janelia Fluor 669, SE is a red fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. It is suitable for live cell imaging. | [Uses]
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1]. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. | [storage]
Store at -20°C | [References]
[1] Jonathan B Grimm, et al. General Synthetic Method for Si-Fluoresceins and Si-Rhodamines. ACS Cent Sci. 2017 Sep 27;3(9):975-985. DOI:10.1021/acscentsci.7b00247 | [Excitation / Emission Maximum]
669 nm/682 nm |
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MedChemExpress
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