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2127150-20-1

2127150-20-1 Structure

2127150-20-1 Structure
IdentificationBack Directory
[Name]

JANELIA FLUOR 669, SE
[CAS]

2127150-20-1
[Synonyms]

JF669, SE
JANELIA FLUOR 669, SE
1-[7-(1-Azetidinyl)-10-[2-Carboxy-5-[(2-(2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl]thio-3,4,6-trifluorophenyl]-9,9-dimethyl-9-silaanthracen-2(9H)-ylidene]azetidinium, inner salt
[Molecular Formula]

C34H30F3N3O6SSi
[MDL Number]

MFCD31619141
[MOL File]

2127150-20-1.mol
[Molecular Weight]

693.77
Chemical PropertiesBack Directory
[solubility ]

Soluble to 20 mM in DMSO
[form ]

Solid
[color ]

Light green to green
Hazard InformationBack Directory
[Description]

Janelia Fluor 669, SE is a red fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. It is suitable for live cell imaging.

[Uses]

Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1]. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
[storage]

Store at -20°C
[References]

[1] Jonathan B Grimm, et al. General Synthetic Method for Si-Fluoresceins and Si-Rhodamines. ACS Cent Sci. 2017 Sep 27;3(9):975-985. DOI:10.1021/acscentsci.7b00247
[Excitation / Emission Maximum]

669 nm/682 nm
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