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2136600-69-4

2136600-69-4 Structure

2136600-69-4 Structure
IdentificationBack Directory
[Name]

2(1H)-Isoquinolinepropanol, β,β-difluoro-1-[4-[2-[3-(fluoromethyl)-1-azetidinyl]ethoxy]phenyl]-3,4-dihydro-6-hydroxy-3-methyl-, (1S,3S)-
[CAS]

2136600-69-4
[Synonyms]

Estrogen receptor antagonist 5
2(1H)-Isoquinolinepropanol, β,β-difluoro-1-[4-[2-[3-(fluoromethyl)-1-azetidinyl]ethoxy]phenyl]-3,4-dihydro-6-hydroxy-3-methyl-, (1S,3S)-
[Molecular Formula]

C25H31F3N2O3
[MOL File]

2136600-69-4.mol
[Molecular Weight]

464.53
Chemical PropertiesBack Directory
[Boiling point ]

618.6±55.0 °C(Predicted)
[density ]

1.230±0.06 g/cm3(Predicted)
[pka]

9.91±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

Estrogen receptor antagonist 5 is a potent antagonist of Estrogen receptor. The estrogen receptor is a ligand-activated transcriptional regulatory protein that mediates induction of a variety of biological effects through its interaction with endogenous estrogens. Estrogen receptor antagonist 5 has the potential for the research of metastatic disease (extracted from patent WO2017174757A1, compound 165)[1].
[References]

[1] Sharada Labadie, et al. Tetrahydroisoquinoline estrogen receptor modulators and uses thereof. Patent WO2017174757A1.
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