| Identification | Back Directory | [Name]
3,4-dihydro-2H-pyrrole-5-carboxylic acid | [CAS]
2139-03-9 | [Synonyms]
Pyrroline-5-carboxylate
1-pyrroline-2-carboxylic acid
3,4-dihydro-2H-pyrrole-5-carboxylic acid
2H-Pyrrole-5-carboxylic acid, 3,4-dihydro- | [Molecular Formula]
C5H7NO2 | [MOL File]
2139-03-9.mol | [Molecular Weight]
113.11 |
| Hazard Information | Back Directory | [Uses]
Pyrroline-5-carboxylate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [Definition]
ChEBI: The product resulting from formal oxidation of DL-proline by loss of hydrogen from the nitrogen and from the carbon alpha to the carboxylic acid, with the formation of a C=N bond. | [IC 50]
Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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