ChemicalBook--->CAS DataBase List--->21416-67-1

21416-67-1

21416-67-1 Structure

21416-67-1 Structure
IdentificationBack Directory
[Name]

4,4'-propylenebis(piperazine-2,6-dione)
[CAS]

21416-67-1
[Synonyms]

RAZOXANUM
Troxozone
Propyliminum
rac-Dexrazoxane
4,4'-(Propane-1,2-diyl)
bis(piperazine-2,6-dione)
-propylenebis(piperazine-2,6-dione)
4,4'-propylenebis(piperazine-2,6-dione)
4,4'-Propane-1,2-diyldipiperazine-2,6-dione
4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
4,4'-propylenebis(piperazine-2,6-dione) USP/EP/BP
4,5,9,10-Pyrenetetrone,2,7-bis(1,6-dimethylethyl)-
4-[3-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
ICRF 159,ICRF159,ICRF-159,Topoisomerase II Inhibitor,Razoxane,RCC,Inhibitor,Topoisomerase,renal cell carcinoma,inhibit
[EINECS(EC#)]

244-379-2
[Molecular Formula]

C11H16N4O4
[MDL Number]

MFCD00430424
[MOL File]

21416-67-1.mol
[Molecular Weight]

268.269
Chemical PropertiesBack Directory
[Melting point ]

237-239°
[Boiling point ]

411.43°C (rough estimate)
[density ]

1.2576 (rough estimate)
[refractive index ]

1.6081 (estimate)
[storage temp. ]

room temp
[solubility ]

DMSO: soluble40mg/mL
[form ]

solid
[pka]

11.00±0.20(Predicted)
[Water Solubility ]

3g/L(25 ºC)
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

TL6389900
[Safety Profile]

Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard InformationBack Directory
[Uses]

Razoxane is an inhibitor of Topo II.
[Definition]

ChEBI: Razoxane is a N-alkylpiperazine.
Spectrum DetailBack Directory
[Spectrum Detail]

4,4'-propylenebis(piperazine-2,6-dione)(21416-67-1)1HNMR
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