| Chemical Properties | Back Directory | [Boiling point ]
448.3±45.0 °C(Predicted) | [density ]
1.08±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C, protect from light | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Liquid | [pka]
11.95±0.46(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
TCO-PEG2-amine contains a click chemistryTCO moiety and a free amine. This reagent can be used to derivatize activated esters or carboxyl groups through a stable amide bond in the presence of of activators EDC. The hydrophilic PEG linker increases the solubility of compounds in aqueous media. | [Uses]
TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001 |
|
| Company Name: |
Xinyanpomei
|
| Tel: |
15850660754 |
| Website: |
http://www.xinyanpomei.com |
|