2143917-62-6

Directory

2143917-62-6 Structure

Identification	Back Directory
[Name] 4-Pyridinecarboxamide, 2-(4-methyl-1-piperazinyl)-N-[6-(1-methyl-1H-pyrazol-4-yl)-3-isoquinolinyl]-
[CAS] 2143917-62-6
[Synonyms] SM08502 Cirtuvivint Cirtuvivint( SM08502) Cirtuvivint (Synonyms: SM08502) 4-Pyridinecarboxamide, 2-(4-methyl-1-piperazinyl)-N-[6-(1-methyl-1H-pyrazol-4-yl)-3-isoquinolinyl]-
[Molecular Formula] C24H25N7O
[MOL File] 2143917-62-6.mol
[Molecular Weight] 427.5

Chemical Properties	Back Directory
[storage temp. ] 4°C, away from moisture and light
[solubility ] DMSO : 12.5 mg/mL (29.24 mM; ultrasonic and warming and heat to 60°C)
[form ] Solid
[color ] Light yellow to yellow

Hazard Information	Back Directory
[Uses] Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor. Cirtuvivint can be used for solid tumors research[1].
[in vivo] Orally administered Cirtuvivint (SM08502) significantly inhibits growth of gastrointestinal tumors and decreased SRSF phosphorylation and Wnt pathway gene expression in xenograft mouse models^[1].
[storage] 4°C, away from moisture and light
[References] [1] Betty Y Tam, et al. The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models. Cancer Lett. 2020 Mar 31;473:186-197. DOI:10.1016/j.canlet.2019.09.009

2143917-62-6 suppliers list

Company Name:	WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel:	17702719238 18971495150;
Website:	http://www.sun-shinechem.com/

Company Name:	Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
Tel:	15317229551
Website:	https://www.ureiko.com

Company Name:	Jinan Jiuli Biotechnology Co. , Ltd.
Tel:	15865264761
Website:	www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm

Company Name:	Hebei Weite Medical Technology Co., Ltd
Tel:	13180081292
Website:	http://www.wetogethermed.com/

Company Name:	Nantong QuanYi Biotechnology Co., Ltd
Tel:	0513-66337626 18051384581
Website:	https://www.chemhifuture.com/

Company Name:	Shanghai Yifei Biotechnology Co. , Ltd.
Tel:	021-65675885 18964387627
Website:	http://www.efebio.com

Company Name:	RD International Technology Co., Limited
Tel:	18024082417
Website:	www.ruidiresearch.com

Company Name:	Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd
Tel:	025-58851090 17714375163
Website:	https://www.aikonchem.com/

Company Name:	Sangon Biotech (Shanghai) Co.,Ltd.
Tel:	400-821-026
Website:	www.sangon.com

Company Name:	Shanghai Yaoheping Biopharmaceutical Technology Co., Ltd
Tel:	021-57540919 13120888836
Website:

Tags:2143917-62-6 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login