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214697-26-4

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214697-26-4 Structure

214697-26-4 Structure
IdentificationBack Directory
[Name]

4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE
[CAS]

214697-26-4
[Synonyms]

ABT 702 dihydrochlor
ABT 702 DIHYDROCHLORIDE
Adenosine Kinase Inhibitor
5-(3-broMophenyl)-7-(6-Morpholinopyridin-3-yl)pyrido[2,3-d]pyriMidin-4-aMine
4-Amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidine
5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-pyrido[2,3-d]pyrimidin-4-amine
Pyrido[2,3-d]pyrimidin-4-amine, 5-(3-bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-
5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine
5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyrido[2,3-d]byrimidin-4-aminedihydrochloride
4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE
5-(3-BROMOPHENYL)-7-[6-(4-MORPHOLINYL-PYRIDIN-3-YL)-3-PYRIDO[2,3-D]PYRIMIDIN-4-AMINE] DIHYDROCHLORIDE
[Molecular Formula]

C22H19BrN6O
[MDL Number]

MFCD03452809
[MOL File]

214697-26-4.mol
[Molecular Weight]

463.33
Chemical PropertiesBack Directory
[Melting point ]

227-245 °C(lit.)
[storage temp. ]

Desiccate at RT
[solubility ]

DMSO: 24 mg/mL
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

ABT 702 Dihydrochloride is employed in the assay for quantitative high-?throughput screening of anti-?hepatitis C virus compounds.
[Biological Activity]

Potent non-nucleoside adenosine kinase inhibitor (IC 50 = 1.7 nM), selective over other sites of adenosine interaction (A 1 , A 2A and A 3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in animal models of pain and inflammation.
Spectrum DetailBack Directory
[Spectrum Detail]

4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE(214697-26-4)1HNMR
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