| Identification | Back Directory | [Name]
4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 2,3,4,5,6-pentafluorophenyl ester | [CAS]
2148295-92-3 | [Synonyms]
4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 2,3,4,5,6-pentafluorophenyl ester | [Molecular Formula]
C20H23F5O7 | [MDL Number]
MFCD29049371 | [MOL File]
2148295-92-3.mol | [Molecular Weight]
470.38 |
| Chemical Properties | Back Directory | [Boiling point ]
485.4±45.0 °C(Predicted) | [density ]
1.300±0.06 g/cm3(Predicted) | [InChI]
InChI=1S/C20H23F5O7/c1-2-4-27-6-8-29-10-12-31-13-11-30-9-7-28-5-3-14(26)32-20-18(24)16(22)15(21)17(23)19(20)25/h1H,3-13H2 | [InChIKey]
NWISPSNLWMLYFW-UHFFFAOYSA-N | [SMILES]
C(OC1=C(F)C(F)=C(F)C(F)=C1F)(=O)CCOCCOCCOCCOCCOCC#C |
| Hazard Information | Back Directory | [Uses]
Propargyl-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG5-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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