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2155855-77-7

2155855-77-7 Structure

2155855-77-7 Structure
IdentificationBack Directory
[Name]

3-amino-1-(2-amino-3-hydroxyphenyl)propan-1-one dihydroiodide
[CAS]

2155855-77-7
[Synonyms]

3-OH-Kynurenamine (dihydroiodide)
3-amino-1-(2-amino-3-hydroxyphenyl)propan-1-one dihydroiodide
1-Propanone, 3-amino-1-(2-amino-3-hydroxyphenyl)-, hydriodide (1:2)
Hazard InformationBack Directory
[Uses]

3-OH-Kynurenamine dihydroiodide is the dihydroiodide form of 3-OH-Kynurenamine (HY-156908). 3-OH-Kynurenamine dihydroiodide is an activator for aryl hydrocarbon receptor (AhR), and thus regulates the immune response. 3-OH-Kynurenamine dihydroiodide upregulates the expressions of Ido1 and Tgfb1, ameliorates the skin inflammation in psoriasis mouse model and kidney damage in nephrotoxic lupus mouse model[1].
[References]

[1] Laura SANTAMBROGIO. Immunoregulatory role of 3-oh-kynurenamine and uses thereof. Patent, WO2019178013A1.
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