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2158297-63-1

2158297-63-1 Structure

2158297-63-1 Structure
IdentificationBack Directory
[Name]

KRAS G12C inhibitor 5
[CAS]

2158297-63-1
[Synonyms]

KRAS G12C inhibitor 5
KRAS G12C inhibitor 11
KRAS G12C inhibitor 5,KRAS G-12C inhibitor 5
[Molecular Formula]

C32H37N7O2
[MDL Number]

MFCD31813717
[MOL File]

2158297-63-1.mol
[Molecular Weight]

551.68
Chemical PropertiesBack Directory
[Boiling point ]

838.6±75.0 °C(Predicted)
[density ]

1.228±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

9.31±0.40(Predicted)
Hazard InformationBack Directory
[Description]

KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].

Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].

[Uses]

KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].
[IC 50]

KRas G12C
[storage]

Store at -20°C
[References]

[1]. John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.

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