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2162120-75-2

2162120-75-2 Structure

2162120-75-2 Structure
IdentificationBack Directory
[Name]

L-Prolinamide, N-(12,12-dimethyl-1,10-dioxo-3,6,11-trioxa-9-azatridec-1-yl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
[CAS]

2162120-75-2
[Synonyms]

JYS007
VH032-PEG2-NH-Boc
L-Prolinamide, N-(12,12-dimethyl-1,10-dioxo-3,6,11-trioxa-9-azatridec-1-yl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
[Molecular Formula]

C33H49N5O8S
[MOL File]

2162120-75-2.mol
[Molecular Weight]

675.84
Chemical PropertiesBack Directory
[Boiling point ]

903.6±65.0 °C(Predicted)
[density ]

1.224±0.06 g/cm3(Predicted)
[pka]

12.22±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

VH032-PEG2-NH-BOC is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-PEG2-NH-BOC will remove the protecting group under acidic conditions and be directly used for PROTAC molecule synthesis. VH032-PEG2-NH-BOC is a key intermediate in the synthesis of PROTAC based on VHL ligand.
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