ChemicalBook--->CAS DataBase List--->2163772-19-6

2163772-19-6

2163772-19-6 Structure

2163772-19-6 Structure
IdentificationBack Directory
[Name]

4-(4-Pyridyl)Benzoic Acid
[CAS]

2163772-19-6
[Synonyms]

5-TAMRA-PEG4-Methyltetrazine
[Molecular Formula]

C42H45N7O8
[MDL Number]

MFCD28385537
[MOL File]

2163772-19-6.mol
[Molecular Weight]

775.86
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard InformationBack Directory
[Description]

TAMRA-PEG4-Methyltetrazine is a fluorescent dye compound which can be labled to other macromolecule via click chemistry with TCO. Rhodamine is a commonly used red fluorescent dye tracer in biology for staining cells, tissues, biomarkers or nanoparticles. It has peak fluorescence emission at 572-575 nm.
[Uses]

TAMRA-PEG4-methyltetrazine is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-methyltetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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