| Identification | Back Directory | [Name]
Acetamide, 2-chloro-N-(decahydro-1-naphthalenyl)- | [CAS]
2164447-18-9 | [Synonyms]
MurA-IN-2
Acetamide, 2-chloro-N-(decahydro-1-naphthalenyl)- | [Molecular Formula]
C12H20ClNO | [MOL File]
2164447-18-9.mol | [Molecular Weight]
229.75 |
| Hazard Information | Back Directory | [Uses]
MurA-IN-2 (compound 37), a chloroacetamide fragment containing a primary aliphatic amine, is a potent MurA inhibitor with an IC50 value of 39 μM. MurA-IN-2 has antibacterial activity and inhibits the bacterial cell wall synthesis[1]. | [References]
[1] Grabrijan K, et, al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Sep 13; 114752. |
|
|