ChemicalBook--->CAS DataBase List--->21646-99-1

21646-99-1

21646-99-1 Structure

21646-99-1 Structure
IdentificationBack Directory
[Name]

TETRAETHYL PYROPHOSPHITE
[CAS]

21646-99-1
[Synonyms]

TETRAETHYL PYROPHOSPHITE
Oxybis(diethoxyphosphine)
Bis(diethoxyphosphino) ether
Tetraethyl pyrophosphite 96%
Tetraethyl pyrophosphite,93%,tech.
Diphosphorous acid tetraethyl ester
TETRAETHYL PYROPHOSPHITE, TECH., 93%
Bis(phosphorous acid diethyl)anhydride
Oxybis(phosphonous acid diethyl) ester
[EINECS(EC#)]

244-494-8
[Molecular Formula]

C8H20O5P2
[MDL Number]

MFCD00009082
[MOL File]

21646-99-1.mol
[Molecular Weight]

258.19
Chemical PropertiesBack Directory
[Appearance]

clear colorless liquid
[Boiling point ]

79-81 °C1 mm Hg(lit.)
[density ]

1.057 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.434(lit.)
[Fp ]

>230 °F
[solubility ]

Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
[form ]

Oil
[color ]

Colourless
Hazard InformationBack Directory
[Chemical Properties]

clear colorless liquid
[Uses]

Tetraethyl Pyrophosphite is used as a reagent in the preparation of peptides and in the phosphonylation of carbonyl compounds.
[Uses]

The product can be used as a reagent for peptide synthesis.
[Application]

Tetraethyl pyrophosphite can be used in peptide synthesis; phosphonylation of ketones, aldehydes, and perfluoroalkyl iodides.
[Preparation]

The most convenient method involves the reaction of diethyl phosphite with diethyl  phosphorochloridite. Diethyl phosphorochloridite (223 g) is added rapidly to a solution of diethyl phosphite (138 g) and  triethylamine (101 g) in benzene (200 ml). The mixture is filtered and the benzene removed by distillation at reduced  pressure. The product is isolated by further distillation at reduced pressure (79-81 °C/0.15 mmHg) in 41% yield.
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
Spectrum DetailBack Directory
[Spectrum Detail]

TETRAETHYL PYROPHOSPHITE(21646-99-1)Raman
TETRAETHYL PYROPHOSPHITE(21646-99-1)FT-IR
21646-99-1 suppliers list
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-81139210 +86-18192627656 , +86-18192627656
Website: https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-219/
Company Name: DAYANG CHEM (HANGZHOU) CO.,LTD
Tel: +86-88938639 +86-17705817739 , +86-17705817739
Website: www.dycnchem.com
Company Name: Energy Chemical  
Tel: 021-021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: Zhengzhou Alpha Chemical Co. LTD  
Tel: 0371-0371-53732842 13383863444
Website: https://www.chemicalbook.com/supplier/23629674/
Company Name: Hubei Shishun Biotechnology Co. Ltd  
Tel: 027-59223025 15107168801
Website: http://www.ss-bio.com/
Company Name: Shaanxi DIDU pharmaceutical and Chemical Co., Ltd  
Tel: 029-029-029-81148696 18161915376
Website: www.dideu.cn
Company Name: Shanghai Yingxin laboratory equipment Co., Ltd  
Tel: 021-021-59178156 15300768757
Website: http://www.yingxinbio.com/
Company Name: Shanghai Guchen Biotechnology Co., LTD  
Tel: 021-34675735 19147740836
Website: http://www.shgcsw-edu.com
Company Name: Merck KGaA  
Tel: 21-20338288
Website: www.sigmaaldrich.cn
Company Name: Santa Cruz Biotechnology Inc  
Tel: 021-60936350
Website: www.scbt.com
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Website: http://www.absin.cn
Company Name: United States Biological  
Tel: 800.520.3011 or 781.639.5092
Website: www.usbio.net
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Website: www.sigmaaldrich.com
Company Name: Acros Organics  
Tel: +32 14/57.52.11
Website: www.acros.be
Company Name: CARBONE SCIENTIFIC CO.,LTD  
Tel: +44(0)870 486 8629
Website: www.carbonesci.com
Tags:21646-99-1 Related Product Information
990-91-0 107-49-3

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.