| Identification | Back Directory | [Name]
L-Alanine, L-alanyl-L-seryl-L-seryl-L-leucyl-L-asparaginyl-L-isoleucyl- | [CAS]
216763-24-5 | [Synonyms]
Skeletal muscle-targeted peptide MSP
L-Alanine, L-alanyl-L-seryl-L-seryl-L-leucyl-L-asparaginyl-L-isoleucyl- | [Molecular Formula]
C28H50N8O11 | [MOL File]
216763-24-5.mol | [Molecular Weight]
674.74 |
| Chemical Properties | Back Directory | [Boiling point ]
1202.1±65.0 °C(Predicted) | [density ]
1.288±0.06 g/cm3(Predicted) | [pka]
3.42±0.10(Predicted) | [Sequence]
Ala-Ser-Ser-Leu-Asn-Ile-Ala |
| Hazard Information | Back Directory | [Uses]
Skeletal muscle-targeted peptide MSP is a 7-amino-acid (ASSLNIA) muscle-targeting peptide (MTP). Skeletal muscle-targeted peptide MSP can target the virus through a different binding ligand to the muscle. Skeletal muscle-targeted peptide MSP can be used for the research of diseases of the heart and skeletal muscles[1][2]. | [References]
[1] Yu CY, et al. A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery. Gene Ther. 2009 Aug;16(8):953-62. DOI:10.1038/gt.2009.59
[2] Qi GB, et al. Self-Assembled Peptide-Based Nanomaterials for Biomedical Imaging and Therapy. Adv Mater. 2018 May;30(22):e1703444. DOI:10.1002/adma.201703444 |
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