| Identification | Back Directory | [Name]
APELIN PRECURSOR (61-77) (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE | [CAS]
217082-57-0 | [Synonyms]
Apelin-17
APELIN-17 (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE
Apelin-17 (human, bovine, mouse, rat),Apelin Precursor (61-77)
PREPROAPELIN (61-77) (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE
APELIN PRECURSOR (61-77) (HUMAN, BOVINE, MOUSE, RAT) TRIFLUOROACETATE
H-LYS-PHE-ARG-ARG-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH TRIFLUOROACETATE
Apelin Precursor (61-77) (huMan, bovine, Mouse, rat), Preproapelin (61-77) (huMan, bovine, Mouse, rat)
Apelin-17 (huMan, bovine, Mouse, rat)
Apelin Precursor (61-77) (huMan, bovine, Mouse, rat), Preproapelin (61-77) (huMan, bovine, Mouse, rat)
Preproapelin (61-77) (human, bovine, mouse, rat), Apelin Precursor (61-77) (human, bovine, mouse, rat)/Apelin-17 (human, bovine, mouse, rat)
Apelin-17 (human, bovine, mouse, rat) trifluoroacetate salt H-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH trifluoroacetate salt
L-Phenylalanine, L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl- | [Molecular Formula]
C96H156N34O20S | [MDL Number]
MFCD09025933 | [MOL File]
217082-57-0.mol | [Molecular Weight]
2138.55 |
| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [form ]
Powder | [color ]
White to off-white | [Water Solubility ]
Soluble to 1.20 mg/ml in water | [Sequence]
H-Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH |
| Hazard Information | Back Directory | [Uses]
Apelin-17(human, bovine) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ[1][2][3]. | [IC 50]
HIV-1; HIV-2 | [storage]
Store at -20°C | [References]
[1] Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun. 1998;251(2):471-476. DOI:10.1006/bbrc.1998.9489
[2] Medhurst AD, Jennings CA, Robbins MJ, et al. Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J Neurochem. 2003;84(5):1162-1172. DOI:10.1046/j.1471-4159.2003.01587.x
[3] Zou MX, et al. Apelin peptides block the entry of human immunodeficiency virus (HIV). FEBS Lett. 2000;473(1):15-18. DOI:10.1016/s0014-5793(00)01487-3 |
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