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2-Oleoxyphenethyl phosphocholin (compound 1b) is a p38 MAPK inhibitor with anticancer activity. 2-Oleoxyphenethyl phosphocholin may bind to the p38 MAPK lipid-binding pocket and has broad-spectrum anti-tumor and lipid-modulating activities[1]. | [References]
[1] Hassan AHE, et al. Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2217695. DOI:10.1080/14756366.2023.2217695 |
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