| Identification | Back Directory | [Name]
N-(1-oxopropyl)-Glycine | [CAS]
21709-90-0 | [Synonyms]
NSC 158539
Propionylglycine
N-Propionylglycin
N-propionylglycine
Tiopronin Impurity C
N-(1-oxopropyl)-Glycine
2-propanamidoacetic acid
glycine, N-(1-oxopropyl)-
2-propionamidoacetic acid
2-(propanoylamino)acetic acid
2-(propanoylamino)ethanoic acid
2-(1-oxopropylamino)acetic acid
N-(1-oxopropyl)-Glycine USP/EP/BP
N-propionylglycine(SALTDATA: FREE) | [Molecular Formula]
C5H9NO3 | [MDL Number]
MFCD09049674 | [MOL File]
21709-90-0.mol | [Molecular Weight]
131.13 |
| Chemical Properties | Back Directory | [Melting point ]
126-127 °C | [Boiling point ]
382.6±25.0 °C(Predicted) | [density ]
1.174±0.06 g/cm3(Predicted) | [storage temp. ]
Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.60±0.10(Predicted) | [color ]
White to Off-White | [Major Application]
clinical testing | [InChI]
1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9) | [InChIKey]
WOMAZEJKVZLLFE-UHFFFAOYSA-N | [SMILES]
OC(CNC(CC)=O)=O |
| Hazard Information | Back Directory | [Uses]
A metabolite of methylmalonic acid and propionic acid in children with methylmalonic acid and propionic acid metabolic disorders. | [Definition]
ChEBI: A N-acylglycine obtained by formal condensation of the carboxy group of propionic acid with the amino group of glycine. | [Biological Activity]
Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. Howeverthe excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme th at catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The level of propionylglycine is elevated in patients with propionic acidemiawhich is an inherited deficiency of propionyl-CoA carboxylase. |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Nextpeptide Inc
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+86-0571-81612335 +8613336028439 |
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http://www.nextpeptide.com/ |
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Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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