| Identification | Back Directory | [Name]
FLUORESCEIN DIPHOSPHATE, TETRAAMMONIUM SALT | [CAS]
217305-49-2 | [Synonyms]
FDP MIAL OTOR Esafofina Otoraplin (OTOR) human FDP, TETRAAMMONIUM SALT Fibrocyte-derived protein fructosc diphosphate sodium Fluorescein (tetraammonium) Fluorescein diphosphate (tetraammonium) Melanoma inhibitory activity-like protein FLUORESCEIN DIPHOSPHATE, TETRAAMMONIUM SALT Fluorescein diphosphate tetraammonium salt?SALE FDP [Fluorescein diphosphate, tetraaMMoniuM salt] FLUORESCEIN DIPHOSPHATE, TETRAAMMONIUM SALT USP/EP/BP fructose-1, 6-diphosphoric acid trisodium salt for injection FDP [Fluorescein diphosphate, tetraammonium salt] CAS 217305-49-2* 3',6'-Bis(phosphonooxy)-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one tetraammonium salt | [Molecular Formula]
C20H17NO11P2 | [MDL Number]
MFCD00278758 | [MOL File]
217305-49-2.mol | [Molecular Weight]
509.3 |
| Hazard Information | Back Directory | [Description]
FDP is used as a fluorogenic alkaline phosphatase substrate. Alternatively, it can also be used to detect phosphatases in a chromogenic mode since the enzymatic product (fluorescein) exhibits a large extinction coefficient (close to 100,000 cm-1mol-1). | [Chemical Properties]
Sodium fructose 1,6-diphosphate is a white or off-white crystalline powder that is free-flowing and highly hygroscopic. It is readily soluble in water but insoluble in organic solvents such as ethanol. It has a slight aroma and a slightly salty taste, and the dried form is stable at room temperature. Fructose 1,6-diphosphate is an important intermediate in glucose metabolism in the human body and a metabolic regulator at the molecular level. Its trisodium salt, this product, can regulate the activity of several enzymes involved in glucose metabolism, increase intracellular concentrations of adenosine triphosphate and creatine phosphate, promote potassium influx, increase the content of diphosphoglycerate in red blood cells, and inhibit the release of oxygen free radicals and histamine. It can mitigate tissue damage caused by ischemia and hypoxia, and is particularly protective against ischemic myocardium. Following intravenous injection, it has a plasma half-life of 10-15 minutes. It is distributed from the blood to tissues outside the circulation, where it is hydrolyzed by phosphatases into phosphate and fructose, with a very small amount excreted in the urine. | [Uses]
Fluorogenic alkaline phosphatase probe. | [Excitation / Emission Maximum]
490 nm/514 nm |
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