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217438-17-0

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217438-17-0 Structure

217438-17-0 Structure
IdentificationBack Directory
[Name]

BENZAMIDE, N-METHYL-N-(2-METHYLPHENYL)-3-NITRO-4-(2-THIAZOLYLSULFINYL)-
[CAS]

217438-17-0
[Synonyms]

SB 268262
(+/-)-SB-273779
SB-268262 >=98% (HPLC)
N-METHYL-3-NITRO-4-(THIAZOLE-2-SULFINYL)-N-O-TOLYL-BENZAMIDE
N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide
BENZAMIDE, N-METHYL-N-(2-METHYLPHENYL)-3-NITRO-4-(2-THIAZOLYLSULFINYL)-
[Molecular Formula]

C18H15N3O4S2
[MDL Number]

MFCD10565932
[MOL File]

217438-17-0.mol
[Molecular Weight]

401.46
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: >5mg/mL
[form ]

powder
[color ]

white to beige
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-36
[Safety Statements ]

26
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

SB 268262 is a calcitonin gene-related peptide receptor antagonist.
[Biological Activity]

SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor. SB-268262 inhibits CGRP bindingand CGRP-mediated stimulation of adenylyl cyclase activity in human neuroblastoma cells with IC50 values of 240 and 830 nMrespectively.
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