| Identification | Back Directory | [Name]
BENZAMIDE, N-METHYL-N-(2-METHYLPHENYL)-3-NITRO-4-(2-THIAZOLYLSULFINYL)- | [CAS]
217438-17-0 | [Synonyms]
SB 268262
(+/-)-SB-273779
SB-268262 >=98% (HPLC)
N-METHYL-3-NITRO-4-(THIAZOLE-2-SULFINYL)-N-O-TOLYL-BENZAMIDE
N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide
BENZAMIDE, N-METHYL-N-(2-METHYLPHENYL)-3-NITRO-4-(2-THIAZOLYLSULFINYL)- | [Molecular Formula]
C18H15N3O4S2 | [MDL Number]
MFCD10565932 | [MOL File]
217438-17-0.mol | [Molecular Weight]
401.46 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: >5mg/mL | [form ]
powder | [color ]
white to beige | [InChI]
1S/C18H15N3O4S2/c1-12-5-3-4-6-14(12)20(2)17(22)13-7-8-16(15(11-13)21(23)24)27(25)18-19-9-10-26-18/h3-11H,1-2H3 | [InChIKey]
YXHLPJQQPOMPGE-UHFFFAOYSA-N | [SMILES]
CN(C(=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)c2nccs2)c3ccccc3C |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-36 | [Safety Statements ]
26 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Uses]
SB 268262 is a calcitonin gene-related peptide receptor antagonist. | [Biological Activity]
SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor. SB-268262 inhibits CGRP bindingand CGRP-mediated stimulation of adenylyl cyclase activity in human neuroblastoma cells with IC50 values of 240 and 830 nMrespectively. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|