Identification | Back Directory | [Name]
hydromorphinol | [CAS]
2183-56-4 | [Synonyms]
Oxymorphol a-Oxymorphol 6a-Oxymorphol 6α-Oxymorphol hydromorphinol 6-Oxymorphol (CRM) 14-Hydroxydihydromorphine AABLHGPVOULICI-BRJGLHKUSA-N 6-Alpha-Hydroxy OxyMorphone 14-Hydroxy-7,8-dihydromorphine 7,8-Dihydro-14-hydroxymorphine Hydromorphinol (1.0mg/ml in Acetonitrile) (5a,6a)-4,5-Epoxy-17-methylmorphinan-3,6,14-triol (5α,6α)-4,5-Epoxy-17-MethylMorphinan-3,6,14-triol Morphinan-3,6,14-triol, 4,5-epoxy-17-methyl-, (5α,6α)- | [EINECS(EC#)]
218-565-9 | [Molecular Formula]
C17H21NO4 | [MOL File]
2183-56-4.mol | [Molecular Weight]
303.36 |
Chemical Properties | Back Directory | [Melting point ]
252-253 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
517.6±50.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [solubility ]
DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml | [form ]
A neat solid | [pka]
9.39±0.60(Predicted) |
Hazard Information | Back Directory | [Description]
6α-Oxymorphol (CRM) (Item No. 25940) is a certified reference material categorized as an opioid. It is a metabolite of oxymorphone (Item Nos. 15911 | ISO60171). 6α-Oxymorphol is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. | [Uses]
A metabolite of Oxymorphone | [Brand name]
Ifex (Bristol-Myers Squibb). | [References]
[1] RICHARD D.S. CARLISS . Receptor reserve reflects differential intrinsic efficacy associated with opioid diastereomers[J]. Pharmacology Biochemistry and Behavior, 2009, 92 3: Pages 495-502. DOI: 10.1016/j.pbb.2009.01.019 [2] BOJAN LALOVIC PHD Evan K M, PHD. Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites[J]. Clinical Pharmacology & Therapeutics, 2006, 79 5: 461-479. DOI: 10.1016/j.clpt.2006.01.009 |
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