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2183440-67-5

2183440-67-5 Structure

2183440-67-5 Structure
IdentificationBack Directory
[Name]

TAMRA hydrazide, 6-isomer
[CAS]

2183440-67-5
[Synonyms]

TAMRA hydrazide, 6-isomer
[Molecular Formula]

C25H25ClN4O4
[MDL Number]

MFCD31580089
[MOL File]

2183440-67-5.mol
[Molecular Weight]

480.95
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMF, DMSO, alcohols
[Appearance]

dark colored solid
Hazard InformationBack Directory
[Description]

TAMRA hydrazide, 6-isomer is a TAMRA dye linker containing a hydrazide group. The TAMRA dye is used in nucleotide labeling and amino acid sequencing Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
[Uses]

TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes[1].
[References]

[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910
[Abs/Em Maxima]

541/567 nm
[Fluoresene quantum yield]

0.1
[Extinction Coefficient]

84000
[CF260]

0.32
[CF280]

0.19
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