2183473-14-3

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2183473-14-3 Structure

Identification	Back Directory
[Name] BDP FL-PEG4-amine TFA salt
[CAS] 2183473-14-3
[Synonyms] BDP FL-PEG4-amine BDP FL-PEG4-amine TFA salt
[Molecular Formula] C24H37BF2N4O5
[MDL Number] MFCD31692221
[MOL File] 2183473-14-3.mol
[Molecular Weight] 510.38

Chemical Properties	Back Directory
[solubility ] Soluble in DMSO, DMF, DCM, low solubility in water

Hazard Information	Back Directory
[Description] BDP FL-PEG4-amine TFA salt is a BDP FL linker containing an amine group and a hydrophilic PEG spacer arm. The amine group makes the compound more reactive toward carboxylic acids, NHS esters and other carbonyl groups. The hydrophilic PEG spacer arm can increase water solubility.
[Uses] BDP FL-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs; Alkyl/ether
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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