ChemicalBook--->CAS DataBase List--->2189684-54-4

2189684-54-4

2189684-54-4 Structure

2189684-54-4 Structure
IdentificationBack Directory
[Name]

Carbamic acid, N-[(1S)-1-[3-bromo-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-, 1,1-dimethylethyl ester
[CAS]

2189684-54-4
[Synonyms]

Carbanic acid,N-[CIS)-1-[3-bromo-6-[3-methyl-3(methyl)sulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-,1,1-dimethylethylester
Carbamic acid, N-[(1S)-1-[3-bromo-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-, 1,1-dimethylethyl ester
[Molecular Formula]

C24H27BrF2N2O4S
[MOL File]

2189684-54-4.mol
[Molecular Weight]

557.45
Chemical PropertiesBack Directory
[Boiling point ]

636.8±55.0 °C(Predicted)
[density ]

1.42±0.1 g/cm3(Predicted)
[pka]

10.37±0.46(Predicted)
[InChIKey]

OBUPKGOLRNAZIS-FQEVSTJZSA-N
[SMILES]

C(OC(C)(C)C)(=O)N[C@H](C1=NC(C#CC(C)(S(C)(=O)=O)C)=CC=C1Br)CC1=CC(F)=CC(F)=C1
Hazard InformationBack Directory
[Description]

(S)-tert-butyl (1-(3-bromo-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)carbamate is a key pharmaceutical intermediate for lenapavir (trade name Sunlenca), used in the synthesis of anti-HIV-1 drugs. Lenapavir is a first-in-class long-acting HIV-1 capsid inhibitor administered subcutaneously, providing a prolonged treatment period, significantly reducing the treatment burden on patients, and exhibiting potent antiviral activity against drug-resistant HIV strains.
[Uses]

(S)-Tert-butyl (1-(3-bromo-6-(3-methyl-3-(methylsulfonyl)but-1-YN-1-YL)pyridin-2-YL)-2-(3,5-difluorophenyl)ethyl)carbamate is a pharmaceutical intermediate compound that can be used in the preparation of HIV inhibitors.
2189684-54-4 suppliers list
Company Name: Unibest Industrial Co.,Ltd.
Tel: +86-0574-27855777 +8618758850676 , +8618758850676
Website: https://www.unibestpharm.com/aboutus.html
Company Name: Hangzhou ICH Biofarm Co., Ltd
Tel: +86-0571-28186870; +undefined8613073685410 , +undefined8613073685410
Website: http://www.ichemie.com/
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-2158073036
Website: www.dakenchem.com/
Company Name: Jinan Carbotang Biotech Co.,Ltd.
Tel: +8615866703830 , +8615866703830
Website: https://www.chemicalbook.com/ShowSupplierProductsList31189/0.htm
Company Name: ChemExpress
Tel: +86-19370970350 +86-021-58950125 , +86-021-58950125
Website: https://www.chemexpress.com
Company Name: Henan Aochuang Chemical Co.,Ltd.
Tel: +86-0371-63689365 +8618638391208 , +8618638391208
Website: http://www.aochuangchem.com/
Company Name: Beijing Toachem Chemical Co.,Ltd
Tel: +8618311365218 , +8618311365218
Website: www.toachem.com
Company Name: Shenzhen Nexcon Pharmatechs Ltd.
Tel: +86-0755-89396905 +86-18025329037 , +86-18025329037
Website:
Company Name: ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Tel: +86-13017695106 +86-13676922317 , +86-13676922317
Website:
Company Name: Shanghai Joy Biotech Ltd.
Tel: +86-15968534750 +86-1358845959750 , +86-1358845959750
Website: www.joybiotech.com
Company Name: Henan Rane Chemical Co., Ltd.
Tel: +8618738066252 , +8618738066252
Website: www.ranechem.com/
Company Name: Nantong Nuotai Biomedical Technology Co., Ltd.  Gold
Tel: 0513-82206272 17706270880
Website: www.noatic.com
Company Name: Shanghai Boc Chemical Co.,Ltd  Gold
Tel: 021-34975603-808 18721111801
Website: http://www.bocchem.com/
Company Name: Shanghai Hope Chem Co., Ltd.,  Gold
Tel: +21-18501659228 18501659228
Website: http://www.hope-chem.com
Company Name: BOYAN PHARMA  Gold
Tel: 18566078841 18566078841
Website: boyanpharma.com/index.php?c=category&id=9
Company Name: Gansu Haotian PharmaTech Co.,Ltd.  Gold
Tel: 17789447501
Website: www.haotianpharmatech.com/
Company Name: Shanghai Haoyuan Chemexpress Co., Ltd.  Gold
Tel: 021-58950125
Website: www.chemexpress.com.cn
Company Name: WuYan Pharmaceutical Technology (Shanghai) Co., Ltd.  Gold
Tel: 13671938079
Website: www.wuyanpharm.com
Tags:2189684-54-4 Related Product Information