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219613-02-2

219613-02-2 Structure

219613-02-2 Structure
IdentificationBack Directory
[Name]

5-Hexenoic acid, 3-[(hydroxyamino)carbonyl]-2-(2-methylpropyl)-6-phenyl-, 2-(2-methylpropyl)-2-(methylsulfonyl)hydrazide, (2R,3S,5E)-
[CAS]

219613-02-2
[Synonyms]

Ro327315
Ro-327315
Ro 327315
Ro 32-7315
Ro 32 7315
5-Hexenoic acid, 3-[(hydroxyamino)carbonyl]-2-(2-methylpropyl)-6-phenyl-, 2-(2-methylpropyl)-2-(methylsulfonyl)hydrazide, (2R,3S,5E)-
[Molecular Formula]

C22H35N3O5S
[MDL Number]

MFCD06198838
[MOL File]

219613-02-2.mol
[Molecular Weight]

453.6
Chemical PropertiesBack Directory
[density ]

1.180±0.06 g/cm3(Predicted)
[pka]

9.26±0.40(Predicted)
Hazard InformationBack Directory
[Description]

Ro 32-7315 is an ADAM17-selective inhibitor.
[Uses]

Ro 32-7315 is a TNF-α converting enzyme (TACE) inhibitor[1].
[References]

[1] Hans Hilpert, et al. Practical approaches to the matrix metalloproteinase inhibitor Trocade? (Ro 32-3555) and to the TNF-α converting enzyme inhibitor Ro 32-7315. Tetrahedron. 2001, 57, 36.
219613-02-2 suppliers list
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