Identification | Back Directory | [Name]
6H-Purin-6-one, 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-, sodium salt (1:1) | [CAS]
219657-36-0 | [Synonyms]
Eprociclovir Na 6H-Purin-6-one, 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-1,9-dihydro-, sodium salt (1:1) | [Molecular Formula]
C11H16N5NaO3 | [MOL File]
219657-36-0.mol | [Molecular Weight]
289.27 |
Hazard Information | Back Directory | [Uses]
Eprociclovir sodium is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir sodium is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir sodium is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir sodium can be used in studies interfered with by sensitive viruses[1]. | [References]
[1] Gandar F, et al. In vitro and in vivo assessment of eprociclovir as antiviral treatment against testudinid herpesvirus 3 in Hermann's tortoise (Testudo hermanni)[J]. Research in veterinary science, 2019, 124: 20-23. DOI:10.1016/j.rvsc.2019.02.001 |
|
|