| Hazard Information | Back Directory | [Uses]
MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer[1]. | [in vivo]
MnTE2-PyP decreases tumor volume and increases survival in vivo mouse model of prostate cancer[1].
MnTE-2-PyP reduces blood glucose and inhibits pro-fibrotic signaling in a diabetic model[1]. | [References]
[1] Arpita Chatterjee, et al. MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses. Redox Biol. 2020 Jul;34:101542. DOI:10.1016/j.redox.2020.101542 |
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