ChemicalBook--->CAS DataBase List--->220352-36-3

220352-36-3

220352-36-3 Structure

220352-36-3 Structure
IdentificationBack Directory
[Name]

(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid
[CAS]

220352-36-3
[Synonyms]

Ticagrelor-22
Ticagerelor Impurity
Ticagrelor Related Compound 28
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid
Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, (1R,2R)-
(1R-2R)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPANECARBOXYLIC ACID CAS 220352-36-3
Ticagrelor impurity 33/(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic acid
[EINECS(EC#)]

1533716-785-6
[Molecular Formula]

C10H8F2O2
[MDL Number]

MFCD20639702
[MOL File]

220352-36-3.mol
[Molecular Weight]

198.17
Chemical PropertiesBack Directory
[Melting point ]

78 - 81°C
[Boiling point ]

308.1±42.0 °C(Predicted)
[density ]

1.435±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
[form ]

Solid
[pka]

4.53±0.10(Predicted)
[color ]

Off-White
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid is an intermediate used to prepare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis. It is also used to synthesize triazolopyrimidine derivatives as P2T receptor antagonists.
Spectrum DetailBack Directory
[Spectrum Detail]

(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid(220352-36-3)1HNMR
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