| Identification | Back Directory | [Name]
1H-Pyrazole-4-carboxamide, 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]- | [CAS]
2204230-40-8 | [Synonyms]
CM121
1H-Pyrazole-4-carboxamide, 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]- | [Molecular Formula]
C24H17FN4O3S | [MOL File]
2204230-40-8.mol | [Molecular Weight]
460.48 |
| Hazard Information | Back Directory | [Uses]
CM121 is an active site-directed reversible ALDH1A2 inhibitor (IC50=0.54 μM；Kd=1.1 μM) with a variety of hydrophobic interactions[1]. | [References]
[1] Chen Y, et al. Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors. ACS Chem Biol. 2018;13(3):582-590 |
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