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22048-97-1

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22048-97-1 Structure

22048-97-1 Structure
IdentificationBack Directory
[Name]

Leptomerine
[CAS]

22048-97-1
[Synonyms]

lepomerine
4(1H)-Quinolinone, 1-methyl-2-propyl-
[Molecular Formula]

C13H15NO
[MDL Number]

MFCD28336213
[MOL File]

22048-97-1.mol
[Molecular Weight]

201.26
Chemical PropertiesBack Directory
[Boiling point ]

300.4±42.0 °C(Predicted)
[density ]

1.063±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

2.56±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Leptomerine, an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer Disease. Leptomerine inhibits acetyl cholinesterase (AChE) with an IC50 of 2.5 μM. Anticholinesterasic activity[1].
[References]

[1] Cardoso-Lopes EM, et al. Alkaloids from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer disease. Molecules. 2010 Dec 13;15(12):9205-13. DOI:10.3390/molecules15129205
Spectrum DetailBack Directory
[Spectrum Detail]

Leptomerine(22048-97-1)1HNMR
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